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Furthermore, with large-scale drug use it is inevitable that PZQ-resistant parasites will evolve, and PZQ resistance has been induced in laboratory infections 12

First, for each metabolite in this set, the feasible flux range of its exchange reaction was computed via FVA

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Ryan PM, Bourdi M, Korrapati MC, Proctor WR, Vasquez RA, Yee SB, et al
Group 3 had 1 male and 11 female participants age 55 (SD 9.1) BMI 28.5 (SD 3.3)
