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Tobacco co-occurs with nearly every other substance use disorder, and F17 codes are reported alongside the other familys codes each substance gets its own code

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Cigarette smoke stimulates alveolar macrophages and dendritic cells to produce chemokines such as macrophage-derived chemokine and thymus- and activation-regulated chemokine, which recruit eosinophils into the lungs [24]

And I'm not making fun of cancer, by the way, or other people with cancer