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Although most of the participants who dropped out of or withdrew from the study prior to V3 smoked usual brand long rod length, a multinomial proportion test found no evidence of significant difference between ULS, ULM, and ULL proportions of dropouts due to lack of power

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6,7,8,9,10,11,12 One strong finding that has emerged is the important role of CYP2A6-mediated nicotine metabolism in predicting smoking intensity (the nicotine uptake from each cigarette), carcinogen exposure and lung cancer risk