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Inhibitory molecules associated with myelin and the glial scar such as myelinassociated glycoprotein (MAG), NogoA, and oligodendrocyte myelin glycoprotein (OMgp), account for the inhibitory activity in the CNS

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Due to its striking phenotype in the ear, and especially the mammalian cochlea, the PCP pathway has been the most studied of the non-canonical Wnt signaling branches

Current technology cannot reliably protect large peptides from enzymatic breakdown across the entire digestive tract at sufficient doses for clinical effect