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While direct evidence linking these specific pouch effects to cardiovascular outcomes is limited in these studies, such cellular pathways (inflammation, oxidative stress) are recognized contributors to cardiovascular pathology, a link extensively discussed for other nicotine products like E-cigarettes (27)

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Treatment options range from improved oral hygiene and quitting tobacco to laser depigmentation and surgery

PLS-DA was carried out in SIMCA 14.1

Lauren Mahesri, RDN, LD, from The Pediatric Dietitian, explained that the connection between smoking and a variety of metabolic disorders such as high cholesterol, insulin resistance, high blood pressure, and type 2 diabetes is well known