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Fortunately, my relative was able to quit smoking, but tragically his wife could not and died in her early 60s of brain and lung cancer

On July 2, Director Hathi responded to the letter in perhaps the most obtuse fashion possible:

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Such sweeping measures indicate a wide appreciation of the health threats posed by cigarettes

A separate study found similar results suggesting an increase in MUC5AC protein levels in culture human bronchial epithelial cells exposed to PG:VG aerosols [37] as well as an increase gene expression for several inflammatory markers including cytokines interleukin-6, interleukin-8 and matrix metalloproteinase-9 (MMP-9), known to play a role in the pathogenesis of COPD [37]