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Chronic exposure to tobacco smoke also triggers epithelial-mesenchymal transition (EMT) through signaling pathways such as Wnt/-catenin and MAPK, transforming normal bladder cells into invasive and metastatic cancer cells

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This development marks a significant turn in the ongoing litigation surrounding the controversial smokeless tobacco alternative

The NLRP3 inflammasome is known to be a molecular protein complex that promotes the maturation of proinflammatory cytokines such as interleukin (IL)-1 and IL-18 (Figure 1 and Figure 2)

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