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Moreover, these drugs combined may cause severe issues, such as clinical depression, after long-term use

The effect of tobacco smoking during pregnancy on plasma oxidant and antioxidant status in mother and newborn

Whether using natural tobacco leaf wraps, flavored, or aged varieties, adhering to the following tips ensures they remain fresh and functional: Store in a Cool, Dry Place : Excess moisture can lead to mold, while high temperatures can dry out the wraps, rendering them brittle and difficult to work with

Retrieved 23 March 2013

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2013Geneva, Switzerland: World Health Organization