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There is some evidence that the deposition of the particles produced by cigarette smoking is different to that due to biomass or occupational exposures as these are mostly inhaled nasally where the filtration efficiency is higher, whereas tobacco smoke is inhaled through the mouth at a high flow rate leading to greater deposition in the lower airways and alveoli [22]

Moreover, there is also data that suggest links long-term vaping to chronic lung disease and asthma

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Tanda G, Di Chiara G (1998)

According to Hughes, J

Some of the most difficult are cravings, irritability, lack of energy/focus, and anxiety