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17.Scientific statement from the VDC Working Group

the item(s) will NOT be shipped and deemed abandoned

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Both cigarette smoking and e-cigarette vaping are known to promote endothelial dysfunction, which is the inability of big blood arteries to open sufficiently to give enough blood to the heart and other tissues

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Plasma samples were spiked with 0.05% aqueous formic acid containing a deuterated internal standard of cotinine, extracted with a solid phase resin, and analyzed using LC-MS/MS via multiple reaction monitoring (MRM) to quantitate cotinine