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The MOE approach considers a reference point (e.g., the NOAEL, no observed adverse effect level) from experimental data, an estimated daily exposure dose to the chemical or additive, and an average adult body weight of 60 kg

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These studies varied in terms of exposure type (active or passive smoking), smoking dose, and study design

Denise Kviatcovsky, Shlomik Itav, Yotam Cohen, Claudia Moresi, Shahar Molina, Niv Ayalon, Shanni Hornstein, Hodaya Karbi, Adi Livne, Aurelie Bukimer, Shimrit Eliyahu-Miller and Alona Metz of the Elinav lab

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But no matter how old you are when you quit, you will always have a longer life expectancy than if you had continued to smoke