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Specifically, in A549 and H1650 cells exposed to e-liquid, expression of mesenchymal markers such as vimentin, fibronectin, zinc finger E-box binding homeobox (ZEB)1, and ZEB2 were induced [26]

Essentially, nicotine activates your body when it doesnt need energy, resulting in heightened stress

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Importantly, the misuse of gabapentinoids administered therapeutically appears minimal and therefore the continued pursuit of these drugs for the management of substance use disorders, including cannabis, is warranted, especially considering that few effective pharmacotherapies exist