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Abbreviations: GP gas phase radicals PP particulate phase radicals TSNA tobacco specific nitrosamines NNK 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone NNN N -nitrosonornicotine PAH polyaromatic hydrocarbons PBN N-tert-butyl--phenylnitrone EPR electron paramagnetic resonance CFP Cambridge filter pad TPM total particulate matter REFERENCES 1.Mohammed MT

Given that it is unethical to perform randomized controlled trials involving exposure to vaping on youth, evidence can only come from observational studies of the population

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