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Time-lag from smoking to peak mortality harm Causes of death changed in their contribution to the excess smoking-mortality over time, consistent with heterogeneity by cause of death 8, 12, 22

and Jones, D.A., 2006

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The surgeon generals report marked an inflection point, the beginning of a concentrated effort to regulate cigarette advertising and legally bar smoking from public spaces in America

These trials consistently show the safety of a negative coronary CT angiogram to identify patients for discharge from the emergency department with low rates of adverse cardiovascular events, at significantly lower cost, and greater efficiency in terms of time to discharge. Coronary CT angiography versus standard of care for assessment of chest pain in the emergency department Cury RC, Budoff M, Taylor AJ J Cardiovasc Comput Tomogr 7(2013):79-82 Together, these trials provide definitive evidence for the use of coronary CTA in the emergency department in patients with a low to intermediate pretest probability of coronary artery disease
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