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[DOI] [PubMed] [Google Scholar] Rezk-Hanna M

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Smoking reduces serum levels of lamotrigine

95 Future studies need to combine single-cell transcriptomics and ubiquitin-modified omics to analyze the dynamic regulatory network of the proteasome, UPS and ALP during aging to ensure the correct synthesis, folding, and degradation of proteins, effectively ameliorating age-related pathologies

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Documented risks include gum recession, oral lesions, cardiovascular effects (blood pressure spikes, elevated heart rate), and strong dependency