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Specifically, in A549 and H1650 cells exposed to e-liquid, expression of mesenchymal markers such as vimentin, fibronectin, zinc finger E-box binding homeobox (ZEB)1, and ZEB2 were induced [26]

Appl In Vitro Toxicol 3:121131 Buscetta M, Vincenzo SD, Miele M, Badami E, Pace E, Cipollina C (2019) Cigarette smoke inhibits the NLRP3 inflammasome and leads to caspase-1 activation via the TLR4-TRIF-caspase-8 axis in human macrophages

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Being crammed together with many hundreds of strangers with varying levels of dysfunction while trying to figure out your own failings creates a particular brand of desperation that can feel like hell on earth