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Because of their smokeless, odorless features, many people believe that these nicotine pouches are a safer alternative to cigarettes

, cited in American Journal of Respiratory and Critical Care Medicine

Additionally, if youve had a heart attack or stroke, you may need to wait up to 6 months before donating

Dimensions: 7008 x 4672 px | 59.3 x 39.6 cm | 23.4 x 15.6 inches | 300dpi Date taken: 26 August 2024

The result is instantaneous, dense vapor production that feels remarkably effortless on the draw

Keywords Theophylline Toxicology Sources: bronchodilator for asthma & COPD Mechanism of Action: Theophylline is methylxanthine (similar to caffiene) & exerts most of its effects by antagonizing adenosine receptors similar to caffiene It can also inhibit phosphodiesterase at toxic concentrations (whether PDE inhibition contributes to its effects in humans is unclear) It affects the cardiovascular (CV), neurological, GI, and metabolic systems Hypokalemia, hyperglycemia, hypercalcemia, hypophosphatemia, and acidosis commonly occur after an acute overdose Medication, diet, and underlying diseases can alter its narrow therapeutic window Adverse effects can be evident at therapeutic serum levels Symptoms: nausea, vomiting, abdominal pain .(Think of an overdose of caffiene) mild metabolic acidosis hypokalemia, hypophosphatemia, hypomagnesemia hyperglycemia sinus tachycardia (& tremors) seizures hypotension arrhythmias Treatment: ABCs Aggressive gut decontamination with repeated doses of activated charcoal & whole bowel irrigation Propranolol or other beta blockers can block a beta-mediated sinus tachycardia & hypotension Phenobarbital is prefered over phenytoin for treatment of convulsions