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A phase 2 trial (SYNERGY-NASH) first demonstrated in vivo that GLP-1RA can achieve histological reversal of hepatic fibrosis in MASLD
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14 Patients with type 2 diabetes who were prescribed semaglutide (either oral or subcutaneous) or lixisenatide were compared to unexposed matched patients
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Of note, randomized trials so far have not demonstrated significant effect of PAP therapy on major cardiovascular outcomes 6,15,16,17,18,19
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Initial evaluations focus on a patient's health history, current medication, and weight goals, determining the best approach
