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Studies on mercapturic acids
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(2020) Diosmin enhances the anti-angiogenic activity of sildenafil and pentoxifylline against hepatopulmonary syndrome via regulation of TNF-/VEGF, IGF-1/PI3K/AKT, and FGF-1/ANG-2 signaling pathways

The mechanism most relevant to MS and its animal model, EAE, involves S1P 1 receptor signaling in astrocytes, which has been demonstrated in conditional null mouse mutants lacking S1P 1 in astrocytes

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