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Butyrate possesses unique cell-signalling properties which have shown effects of decreasing insulin resistance in humans, increasing GLP1 production by intestinal cells & the liver, while also sensitizing our body to the effects of GLP-1 [3]

Limitations The major limitations of the studies that are included in this systematic review are the enrollment of healthy subjects and insufficient data in conditions that might affect pharmacokinetics (e.g., kidney dysfunction)

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The Phase III trial of this pipeline drug for treating type 2 diabetes mellitus, non-alcoholic fatty liver disease, and obesity started on August 28, 2023

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