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[PubMed: 2136949] Crawley HF, While D

This disparity may be due to the use of different species between studies (PMI typically used the A/J or Apo E -/- mouse in their studies compared to the Sprague-Dawley rat, CD-1 mouse or C57BL/6NCr mouse used in the independent studies) and/or use of different exposure methodologies

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Four snus products assessed in this study contained a relatively high level of sucralose (0.691.32%, w/w), and three of the four also contained aspartame (0.007590.0128%, w/w)