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Quantifying the relationship between smoking and various important health outcomesin particular, highlighting any significant doseresponse relationshipsis crucial to understanding the attributable health risk experienced by these individuals and informing responsive public policy

In terms of tobacco cards and collectibles, one can argue that the true historical value can only be measured when it is put into context with the item's age, historical or cultural significance, and one's understanding of the period

Botello-Harbaum M, Haynie D, Iannotti R, Wang J, Gase L, et al

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Tobacco that's vacuum sealed will age and ferment, but at a slower rate, and it will experience less change compared to tobacco that's exposed to more air, whether in the original tin or a different container