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Increase risk of growth restriction and lower birth weight

Once inhaled, reactive electrophiles, such as flavorings commonly used in e-liquids, activate TRPA1 by covalent modification of cysteine residues, altering protein complex conformation and facilitating inward flow of cations [116118]

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Another study further recapitulated these findings, however in the context of very specific flavoring compounds such as cinnamaldehyde [76]

Tobacco Control, 24 (Suppl 2), ii42ii49

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