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NICE recommends disease-modifying antirheumatic drugs (DMARDs) such as methotrexate as first-line treatment, with biologic therapies (TNF inhibitors, IL-6 inhibitors) or JAK inhibitors for patients with inadequate response

For tirzepatide, it might be 2.5 mg weekly

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The primary limitation of FAERS is its dependence on voluntary adverse event reporting, which restricts its ability to comprehensively document all occurrences

Options for prandial glucose management in type 2 diabetes patients using basal insulin: addition of a short-acting GLP-1 analogue versus progression to basal-bolus therapy

23 Eating past this point can lead to significant discomfort and worsen side effects like nausea or vomiting