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This article presents the current state of knowledge on mitochondrial damage mechanisms in HI and discusses potential therapeutic strategies, such as modulators of mitochondrial dynamics, antioxidant compounds, or inhibitors of specific mitochondrial pathways

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Reactive oxygen species and thiol antioxidants, including glutathione (GSH), regulate innate immunity at various levels

A greater reliance on fat for energy can result in a sparing of muscle, an enhancement of exercise performance and a reduction in stored body fat