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Non-Alcoholic Fatty Liver Disease (NAFLD) in children and adolescents with Prader-Willi Syndrome (PWS)

The primary concern is not direct drug transfer, but indirect effects: tirzepatide-induced caloric restriction could reduce milk supply, and the appetite suppression might prevent mothers from consuming the extra 300-500 calories per day that breastfeeding demands

doi: 10.1038/mt.2008.198

Discontinuation decisions should be individualised and made in consultation with your prescribing clinician, particularly for diabetes management

While take-up is uncertain, interest in the program among potentially eligible Medicare beneficiaries is likely to be strong

From a translational standpoint, catestatin may be more tractable as a pathway biomarker or as a guide for targeting autonomic dysregulation rather than as a direct peptide therapeutic