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Yes, typically

doi: 10.1016/j.arth.2023.12.023

So when youre taking a GLP 1, youre getting a much higher longer lasting version of what your body produces, and it has to reach the brain through the gut brain barrier

Most patients using GLP-1 agonists achieve significant weight loss

Food and Drug Administration (FDA) and the European Medicines Agency (EMA) to treat diabetes for more than a decade and has recently been authorized to treat overweight and obesity (FDA 2021, EMA 2022) [1]

At higher doses, the glucagon receptor activation may actually help preserve lean mass through increased protein turnover and growth hormone modulation, but the data on this is still emerging