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Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because the serum concentration of thyroid-binding globulin increases with use of COCs [see Warnings and Precautions (5.12)]

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Mona, the ex-wife of ad executive Roger Sterling (John Slattery), is played by Slattery's actual wife, Talia Balsam, according to the Chicago Tribune

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Smoking has been long-known to negatively impact hearing health