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Smoking also constricts your blood vessels, which can interfere with blood flow to the brain and lead to damage over time

2022 May 1;33(3):431-440

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They were using the EC for 19 months, while 20 of them reported that they had quit smoking within less than 1 month initiation of EC use
High blood pressure : Smoking causes blood vessels to constrict and harden more quickly, significantly raising the risk of complications like heart attacks, kidney failure, and strokes
