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Nonetheless, most studies on e-cigarettes have only explored short-term effects, and more longitudinal research is needed to fully assess their long-term impact, especially among dual users of cigarettes and e-cigarettes 26

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The associations between smoking and overlaps of gastroesophageal reflux, functional disorders, and IBS in Japanese adults were significantly stronger in those who smoked one or more packs per day than in those who smoked less 30

doi:10.1002/14651858.CD001009

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Past studies have shown that increased cases of stroke and heart disease are being reported among young persons (Fox, 2018)