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Once addiction takes hold, users find themselves compelled to use nicotine to avoid withdrawal symptoms and to maintain the pleasurable effects, creating a reinforcing cycle of dependence

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Do you smoke more frequently during the first hours after waking than during the rest of the day

2003), Lessov-Schlaggar and colleagues (2008) found that while higher levels of nicotine dependence among adolescents were associated with smoking trajectories marked by heavier smoking, there was no relationship between quantity/frequency of cigarette use during adolescence and lifetime levels of nicotine dependence

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In Tobacco control in China