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These trials have shown reductions in heart failure symptoms and physical limitations and greater improvement in exercise function and have led to growing interest in new ways to address HFpEF, a condition with limited guideline direct medication therapy compared to heart failure with reduced ejection fraction (HFrEF)

This fluid intake reduction may lead to increased thirst as the body tries to compensate for the lower water intake

There were 93 events in the smaller GLP-1 group, compared with 88 events in the twice-as-big non-GLP-1 group, yielding a 0.2% vs

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These symptoms persist even after controlling for physical activity and BMI, pointing to an independent role for metabolic dysfunction in shaping affective symptomatology

2021;16(8):e0255726