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Clinical studies evaluated the neurotoxic effects of tobacco smoking on the brain, and also evaluated the cognitive and behavioral assessments, as well as neuroimaging measures in the human brain, and have established that tobacco smoking decreases brain volume, increases neuro-inflammation and oxidative stress but enhances cognition and neural efficiency (4)

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Randomized trial of the effectiveness of combined behavioral/pharmacological smoking cessation treatment in Syrian primary care clinics

(67) suggested that the blood lead level was significantly associated with the number of decayed teeth for both deciduous and permanent teeth in all age U.S

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doi:10.1371/journal.pmed.1000216