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It was conducted on 99 women divided into 3 groups

Initial observations described no differences in endothelial-dependent dilation between habitual users of combustible tobacco products, users of electronic cigarettes, dual users, and non-users [116, 120], although lower endothelial cell nitric oxide production has been identified in users of ENDS and users of combustible tobacco products when compared to non-users [120]

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On July 27, 1965, President Lyndon Johnson signed legislation requiring warning labels on packages of cigarettes

It's worth noting that while nicotine itself is not considered to be carcinogenic, it is highly addictive and can have a range of negative health effects