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The therapeutic effects of Clostridium and their metabolites (e.g., SCFAs, butyrate, PCS, and vitamin K2) are mediated through a synergistic network of mechanisms, with precise correction of immune dysregulation standing as the most pivotal value

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Favorable outcomes were defined as modified Rankin Scale(mRS) 02 at 90 days
In longitudinal, analyzed pre-RA patients of Erlangen were followed for the later development of RA

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