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In a study focusing on primary microglia cells treated with LPS, the anti-inflammatory PQQ pretreatment significantly reduced the production of NO, PGE2, and inflammatory cytokines (iNOS, COX-2, TNF-a, IL-1b, IL-6, MCP-1, and MIP-1a) (Brodzikowska et al., 2022)

doi: 10.2174/1568026619666181130111202 24 ButrymARybkaJacinaPGburaKFrontkiewiczDBogunia-KubikKet al

doi: 10.1016/j.ecl.2007.04.008

Rabbit gastric extract 15 (RGE 15) was purchased from Lipolyltech (lot number 1201, France)

Because Receptor Grade IGF-1 LR3 from Core Peptides ships with a lot-specific COA, it slots cleanly into studies that demand reproducibility documentation