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This report was followed by two publications: a meta-analysis (Prochaska & Hilton, 2012) and the latest FDA (2013) report

But, Cassels-Smith assured that SyNic was safe, as it is manufactured under strict drug standards at an FDA-approved facility, resulting in a product whose pure nicotine content is greater than 99.95%, the remaining 0.05% being made up primarily of myosmine