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15, 2015 smoking/smoking-facts/whats-in-a-cigarette.html

Barten Holiday, Texnotamia (1630)

By the time we figured out the harms of cigarettes, we had tens of millions of addicts, and it was politically impossible to do something about it, says Chris Bostic, the deputy director for policy at the advocacy group Action on Smoking and Health

[44] Mesnage, R., Renney, G., Sralini, G

The limited existing data that are publicly available on cigarette consumption have been inappropriate for quasi-experimental impact evaluations (modelled data), held privately by companies (proprietary data), or widely dispersed across many national statistical agencies and research organisations (disaggregated data)
But from propaganda going around at the time, it could be inferred that it had much more to do with the thickness and smell of the smoke being annoying