mental effects of cigarettes smoking We're often told about how smoking affects your physical health Tobacco/Nicotine - Rutgers Addiction Research

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The reward circuit eventually adapts to the extra dopamine caused by the drug, becoming steadily less sensitive to it

[DOI] [PMC free article] [PubMed] [Google Scholar] [251].Tellez-Plaza M, Tang WY, Shang Y, Umans JG, Francesconi KA, Goessler W, Ledesma M, Leon M, Laclaustra M, Pollak J, Guallar E, Cole SA, Fallin MD, Navas-Acien A, Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samples, Environ Health Perspect, 122 (2014) 946954