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Description
These include leveraging natural GLP-1 inducers, offering reduced portion sizes, developing GLP-1 companion products, and expanding menu and shelf options to meet evolving consumer demands

SGLT2 inhibitors were chosen as the comparator given they are guideline-recommended second-line glucose-lowering medication and share similar cardiovascular benefits with GLP-1RA, which helps reduce confounding by indication

How have Medicaid prescriptions and gross spending on GLP-1s changed in recent years

FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss
What are the Results of GLP-1 for Weight Loss

Phentermine is also a reasonable first-line option for younger patients without cardiovascular risk factors who want to try medication-assisted weight loss without committing to a more intensive and expensive regimen
