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Beyond its direct systemic toxicological effects, smoking exerts a profound impact on host-associated microbial communities across multiple body sites (Fig
FDA (2018), US Food and Drug Administration, Premarket Tobacco Product Applications and Recordkeeping Requirements. US Food and Drug Administration, Regulation and Enforcement of Non-Tobacco Nicotine (NTN) Products, November 6, 2023, Juul Labs, Juul Labs Statement on FDA Marketing Authorizations, press release, July 17, 2025,
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