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Clinical experience suggests that tiredness may be particularly noticeable during the initial weeks of treatment

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( a - d ) Observed data for participants in the full analysis set treated with semaglutide 2.4 mg (a, c) or placebo (b, d) during the in-trial period

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While safety monitoring was comprehensive, the trials were not specifically designed to detect rare adverse effects that might occur at rates lower than 1-2%, which would require much larger participant numbers

Maintaining a robust immune system is important for overall health and can indirectly impact performance by reducing the risk of illness and fatigue