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1 2 "Do electronic cigarettes impart a lower potential disease burden than conventional tobacco cigarettes?: Review on e-cigarette vapor versus tobacco smoke"

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They have recently reported that not only CD5 + and Foxp3 + B lymphocytes are enriched with a high amount of 7nAChR, even it is necessary for the formation, induction, and functioning of regulatory B lymphocytes [148]

Heavy smoking in adolescents with BD also paves the way to heavier marijuana use, illicit drug use disorders, and poorer overall functioning (43, 44), more agitation and impulsivity (45, 46), more hospitalizations, lower functionality and more suicide attempts (47, 48)

This could be so because smokers are less motivated to seek a non-nicotine reward compared to the cigarettes, and this gap only increases when they stop smoking