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A separate ligament study (Cerovecki et al., 2010, Journal of Orthopaedic Research ) reported improved medial collateral ligament healing in rats over 90 days post-transection, with effective dosing observed across intraperitoneal, oral, and topical routes

For research use, the more controlled setup is a dedicated refrigerator with a thermometer or data logger, a stable shelf location, and a box that protects the vial from light

Thus, mesenchymal cells are necessary targets of TNF- in the development of spondyloarthritis-related disorders [27]

These mechanisms are complementary