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Basic chemical constituents of tobacco leaf and differences among tobacco types

We assessed the effects of instrumental variables for genetically influenced body mass index (BMI, 1244 SNPs) (Pulit et al., 2019) [31], waist-to-hip ratio (WHR, 621 SNPs) (Pulit et al., 2019) [31], Depression (58 SNPs) (Meng et al., 2024) [34], Type 2 Diabetes (T2D, 401 SNPs) (Vujkovic et al., 2020) [32], coronary artery disease (CAD, 208 SNPs) (Van Der Harst and Verweij, 2018) [33], serum Calcium level (225 SNPs) (Sinnott-Armstrong et al., 2021) [35], serum Vitamin D level (98 SNPs) (Sinnott-Armstrong et al., 2021) [35], Testosterone level (95 SNPs) (Sinnott-Armstrong et al., 2021) [35], and bone mineral density (BMD, 896 SNPs) (Morris et al., 2019) [36] for blood trait effects