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The slit diaphragm, a specialized intercellular junction, is structured as a cholesterol and sphingolipid-enriched lipid raft. Cholesterol is 58 times more concentrated in rafts than in the rest of the podocyte membrane

Elimination of drug from the body may involve processes occurring in the kidney, the lung, the liver, and other organs

Muggeridge DJ, Howe CC, Spendiff O, et al

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