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Risks are minimal but may include injection-site irritation or rare allergic reactions
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Economic Literature Review An economic literature search was first conducted on October 9, 2012, and a second search was conducted on June 3, 2013, to update the literature

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Reactions were performed with 0.5 M catechol substrate COMT-S01, 1 M radiolabelled S-adenosyl-L-[methyl- 3 H] methionine (SAM) co-substrate, and recombinant human COMT enzyme
