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PMID 19959701

It balances quantity and portability

A cardiovascular stressor raising blood pressure and heart rate

And we already have trouble getting people to use nicotine patches, just putting one on every day. The hurdles The major challenge now is not so much developing new treatments but getting people to use existing treatments more effectively, says West

Nicotine, alongside many different synthetic substances, connects itself to the tar inside the smoke and is consumed by the lungs when the smoke contacts tissue cells

Cliff reminded me always to light a pipe with a soft flame, never a torch, as too strong a flame can easily damage a pipe