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Notwithstanding, despite the plausible pathophysiological relations, there is little clinical evidence proving this association between smoking and CR

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9 Figure 3.36.1 Risk of heart disease among those that smoke 1 cigarette per day compared to those that smoke 20 cigarettes per day Source: based on Hackshaw et al, 2018 8 Since the 2018 meta-analysis, a prospective study of 188,167 cardiovascular disease (CVD)- and cancer-free individuals aged 45 years and older from the NSW general population (the 45 and Up study) revealed similar findings