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Nicotine activates an innate, anti-inflammatory pathway via the macrophage 7-nicotinic acetylcholine receptor, and interruption of this pathway exacerbates nicotine-associated inflammation and insulin resistance in mice [116], which would be consistent with a co-existing anti-inflammatory effect of nicotine on obesity-related inflammation [117]
Kayyali US, Budhiraja R, Pennella CM, et al
Nicotine side effects: What are they
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Tobacco should be no different. Smoking might not be surging statistically, but culturally, its back on the radar
